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Istent with two-hit genetic models for various diseases, which indicate that differentially greater severity may actually indicate unique pathogenic processes.29 Findings also raise questions regarding the ODD diagnosis, given that youth meeting the 3-symptom criteria for AIS would not meet DSM criteria for ODD without a fourth symptom. However, the results of previous work30,31 indicate that you
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E 1. Intravenous immunoglobulin (IVIG) inhibits immune-mediated demyelination in organotypic cerebellar slice culture (OSC). OSC have been treated as indicated and green fluorescent protein (GFP)-expression was assessed in living OSC making use of a fluorescence microscope 1 and two days immediately after the induction of demyelination. Quantification was performed with Image J Computer software.
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Gnosis of ODD with fewer than 4 ODD symptoms. Nevertheless, all youth with 3 AIS also exhibited at least one NS in the present sample. Given that the DSM model may under-identify youth with impairing ODD,30,31 future research should evaluate the prevalence of youth with AIS who do not meet criteria for ODD, as well as multiple models for considering ODD symptoms and diagnoses (e.g., DSM, ICD). Ac
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