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Leukocyte entry into the brain parenchyma involves two differently regulated steps: migration of leukocytes across the endothelium in to the perivascular space and progression across the glia limitans in to the brain parenchyma. Within a murine model of a number of sclerosis, experimental autoimmune encephalomyelitis (EAE), induction of illness symptoms happens only upon immune cell penetration o
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Is still the most lethal gynecologic malignancy worldwide. Although most ovarian carcinoma cells are initially sensitive to chemotherapy, there is always a small population cells that always survives and initiates new tumors which causes recurrence [31]. The verification of tumor heterogeneity further enhances the hypothesis of CSCs. Compelling evidence has shown that ovarian carcinomas with enri
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