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Was 0.507 year to 0.793 year.Huang et al. BMC Cancer (2015) 15:Page 4 ofFig. 1 ALDH1 expression in ovarian carcinoma cells and stromal cells. a A poor differentiated ovarian carcinoma showed negative immunostaining in tumor cells for ALDH1, while most of the stromal cells surrounding tumor cells were strongly positive (100?. b High magnitude was used in the same case in A, showing clear negative
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Is still the most lethal gynecologic malignancy worldwide. Although most ovarian carcinoma cells are initially sensitive to chemotherapy, there is always a small population cells that always survives and initiates new tumors which causes recurrence [31]. The verification of tumor heterogeneity further enhances the hypothesis of CSCs. Compelling evidence has shown that ovarian carcinomas with enri
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